What Are the Signs and Symptoms of Lupus Nephritis?

In the early stages of lupus nephritis, there are very few signs that anything is wrong. In fact, some patients have no specific symptoms. Kidney problems often start around the same time that lupus symptoms appear.

The first symptoms of lupus nephritis are often:

Fatigue Weight gain
Swelling, usually in legs, feet, or ankles Foamy, bubbly, or frothy urine

Clinical signs of lupus nephritis include:

  • Leakage of a high level of protein into the urine (a condition known as proteinuria). Every person with lupus nephritis has proteinuria. Extra protein in the urine shows up in a clinical laboratory urine test.
  • Leakage of blood into the urine (a condition known as hematuria)
  • High blood pressure
  • Inflammation of the kidneys
  • Scarring of the kidneys

Be sure to always discuss signs and symptoms with your doctor.

Guide to Talking with Your Doctor

Make the most of your healthcare appointments. Download this helpful discussion guide and bring it with you to your next doctor's visit.

Download Guide

Stay Connected. Stay Informed.

Sign up to receive:

  • Ongoing news and updates about lupus nephritis
  • A USB drive that contains helpful printable resources

Register Now